Diseases such as covid-19 and influenza can be fatal due to an overreaction of the body’s immune system called a cytokine storm. Cytokines are small proteins released by many different cells in ...

These molecules positively and negatively regulate macrophage and dendritic-cell activation ... and their role in the immune system and propose a cohesive model of how cytokine signalling ...

Many of the cells in the innate immune system produce cytokines or interact with other cells directly to activate the adaptive immune system. In cancer cells, mutations can lead to expression of tumor ...

Systemic sclerosis is an autoimmune disease that primarily causes inflammation of the skin, as well as internal organs such ...

This system uses excellent ... management system Cytokines - low molecular weight proteins or minor polypeptides - play significant roles in transmitting data between cells and controlling immune ...

For all the mysteries that remain about the novel coronavirus and the COVID-19 disease it causes, scientists have generated an incredible amount of fine-grained knowledge in a surprisingly short time.

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also — in a particular subset of T ...

Messenger proteins, known as pro-inflammatory cytokines, are released by immune cells, to signal the danger and recruit help, and our immune system responds to neutralize the threat. During this ...

Cytokines released in the blood may lead to signs ... neurotoxicity syndrome (ICANS), which is a neurological side effect of CAR-T cell therapy during which the immune system attacks the nervous ...

The most frequent of these immune-mediated toxicities are cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity ... switch off the immune system, the most common ...

Notably, cancer-associated fibroblasts (CAFs), tumor-associated macrophages (TAMs), and immune suppressive cytokines ... immune system's capacity to identify and eradicate tumor cells, presenting ...

Immunotherapy holds great promise for the future of cancer treatment. By harnessing a patient’s own immune system to target ...