Dr. Rebecca Crews from Renue By Science, LLC, outlines a century of NAD+ insights driving aging science and, innovative ...
Repurposing of a drug designed for pain relief can quickly and reversibly slow biochemical and metabolic activities in cells and organs and could facilitate organ transplantation and prevent tissue ...
BACKGROUND: Endothelial cells (ECs) use glycolysis to produce energy. In preclinical models of peripheral arterial disease, further activation of EC glycolysis was ineffective or deleterious in ...
Kynurenine, a tryptophan metabolite, slows astrocyte glycolysis in AD models ... and that without this pathway, effector function and phagocytosis petered out (Minhas et al., 2019). To learn whether ...
Although differentiation and activity of bone-forming osteoblasts are regulated at various levels, there is ample evidence ...
In summary, our findings indicate that the TIPE/PKM2/HIF-1α signaling pathway plays a pivotal role in promoting cancer stem cell properties by facilitating the glycolysis, which would provide a ...
Metabolic rewiring is essential for osteoclast differentiation and bone resorption. This study shows that glutaminolysis ...
PFAS (per- and polyfluoroalkyl substances) earned the nickname "forever chemicals" because they don't break down naturally.
Using cutting-edge bioinformatics techniques for gene identification and sequencing, researchers are comprehensively mapping signaling pathway distributions in both normal and acne-affected skin.
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