Sickle cell trait (SCT) differs vastly from sickle cell disease. SCT is a genetic condition when someone inherits one sickle ...

For people with SCD, hemoglobin S (a mutated protein that transports oxygen) causes red blood cells to become curved ...

An inherited blood disorder, sickle cell disease can be managed with several treatment options to reduce painful episodes and ...

Patients with sickle cell anemia (SCA) and persistent albuminuria (PA) exhibited significantly higher levels of urinary ...

About 100,000 Americans, mostly Black, have sickle cell disease, shortening lifespans, delaying puberty, damaging spleens and ...

The incidence of stroke continues to increase for adults and children living with sickle cell disease (SCD) despite the Stroke Prevention Trial in Sickle Cell Anemia (STOP) establishing standards of ...

GRANDVIEW, Mo. — Ten-year-old Saladin "Bam" Anderson is a sickle cell patient who held his second Sickle Cell Awareness Month ...

Pauling dubbed sickle cell anemia a “molecular disease.” That framing effectively launched the biomedical era of newly powerful laboratory research. Mark T. Gladwin, a longtime sickle cell ...

INDIVIDUAL case reports 1–12 of salmonella osteomyelitis in patients with sickle-cell anemia have appeared in the literature since 1925. In 1951 Hodges and Holt 13 cited 5 cases of Salmonella ...

It’s been almost a year since the Food and Drug Administration approved the first genetic treatments for sickle cell disease.

The quality of life of patients with sickle cell anemia is severely compromised similar to or even worse than patients with other chronic diseases such as arthritis. Patients who responded to ...

What if hemoglobins clumped together? This is what happens in sickle cell disease. Sickle cell arises from a single point mutation in the human genome. That means that one DNA base pair in the HBB ...