Protoporphyrin IX - Wikipedia
WEBProtoporphyrin IX is an organic compound, classified as a porphyrin, that plays an important role in living organisms as a precursor to other critical compounds like heme (hemoglobin) and chlorophyll. It is a deeply colored solid that is not soluble in water. The name is often abbreviated as PPIX.
Protoporphyrin (Blood) - Health Encyclopedia - University of …
WEBThe protoporphyrin test is used to diagnose blood problems caused by lead. The test can show lead exposure or lead poisoning. Lead poisoning is extremely dangerous because lead can damage organs throughout the body.
Erythropoietic Protoporphyria - StatPearls - NCBI Bookshelf
WEBFeb 16, 2023 · Erythropoietic protoporphyria (EPP) is an inherited condition resulting in the accumulation of protoporphyrins in red blood cells that causes acute, painful, non-blistering photosensitivity and potential liver disease. [1]
Protoporphyrin IX: the Good, the Bad, and the Ugly - PMC
WEBJul 27, 2015 · Protoporphyrin IX (PPIX) is ubiquitously present in all living cells in small amounts as a precursor of heme. PPIX has some biologic functions of its own, and PPIX-based strategies have been used for cancer diagnosis and treatment (the good).
Protoporphyrin - an overview | ScienceDirect Topics
WEBThe protoporphyrin found in the erythrocytes of patients with both iron deficiency and lead intoxication is the zinc chelate, zinc protoporphyrin. The compound initially formed is free protoporphyrin base; this compound is bound at the heme pocket where it progressively chelates zinc nonenzymatically while in the circulation.
protoporphyrin IX | C34H34N4O4 | CID 4971 - PubChem
WEBProtoporphyrin is a cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
A Recap of Heme Metabolism towards Understanding Protoporphyrin …
WEBJul 19, 2022 · Heme, protoheme or iron protoporphyrin IX are a prosthetic complex of ferrous iron and PpIX that comes into play in major processes such as electron transfer chains, respiratory complexes, oxygen transport and storage of metal ions.
Protoporphyrin - an overview | ScienceDirect Topics
WEBProtoporphyrin is a demetallated porphyrin of protoheme that is an important bioactive compound found in hemoglobin, and its zinc complex is used as a medicine. AI generated definition based on: Journal of Fluorine Chemistry, 2001
Protoporphyrin - an overview | ScienceDirect Topics
WEBPorphyrins are aromatic macrocyclic structures derived from a basic structure composed of four pyrrole rings joined by methylene bridges (Fig. 1).
The Red Color of Life Transformed - Chemistry Europe
WEBFeb 25, 2020 · Protoporphyrin IX (PPIX) is the porphyrin scaffold of heme b, a ubiquitous prosthetic group of proteins responsible for oxygen binding (hemoglobin, myoglobin), electron transfer (cytochrome c) and catalysis (cytochrome P450, catalases, peroxidases).